Protein X is a soluble, secreted protein. It has an N-terminal ER import sequence that allows it to be translocated into the ER during translation.
Protein X is a soluble, secreted protein. It has an N-terminal ER import sequence that allows it to be translocated into the ER during translation. If you altered the sequence of this protein in the following ways, would it affect its final destination? If yes, explain why and what the new destination would be. If not, explain why. 1) You add an ER retention signal to the protein. 2) You add a nuclear localization signal to the end of the protein sequence.
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